Version 5.4
Bos taurus Gene: ACADSB
Summary
InnateDB Gene IDBG-640779.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ACADSB
Gene Name Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000018041
Encoded Proteins
IDBP-693075
Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000196177:
Short/branched chain acyl-CoA dehydrogenase(ACADSB) is a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. Substrate specificity is the primary characteristic used to define members of this gene family. The ACADSB gene product has the greatest activity towards the short branched chain acyl-CoA derivative, (S)-2-methylbutyryl-CoA, but also reacts significantly with other 2-methyl branched chain substrates and with short straight chain acyl-CoAs. The cDNA encodes for a mitochondrial precursor protein which is cleaved upon mitochondrial import and predicted to yield a mature peptide of approximately 43.7-KDa. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 26:43134415-43184345
Strand Forward strand
Band
Transcripts
ENSBTAT00000024017 ENSBTAP00000024017
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003995 acyl-CoA dehydrogenase activity
GO:0016491 oxidoreductase activity
GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors
GO:0050660 flavin adenine dinucleotide binding
Biological Process
GO:0006629 lipid metabolic process
GO:0006631 fatty acid metabolic process
GO:0008152 metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000196177
View Gene Order
ENSMUSG00000030861
View Gene Order
Pathways
NETPATH
REACTOME
REACT_226362
Metabolism of amino acids and derivatives pathway
REACT_216656
Branched-chain amino acid catabolism pathway
REACT_219139
Metabolism pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_197
Branched-chain amino acid catabolism pathway
REACT_13
Metabolism of amino acids and derivatives pathway
REACT_111217
Metabolism pathway
REACT_188937
Metabolism pathway
REACT_232845
Metabolism of amino acids and derivatives pathway
REACT_254568
Branched-chain amino acid catabolism pathway
KEGG
hsa00280
Valine, leucine and isoleucine degradation pathway
hsa00071
Fatty acid degradation pathway
mmu00280
Valine, leucine and isoleucine degradation pathway
mmu00071
Fatty acid degradation pathway
INOH
PID NCI
Cross-References
SwissProt Q5EAD4
TrEMBL
UniProt Splice Variant
Entrez Gene 504301
UniGene Bt.23226
RefSeq NM_001017933
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC122698 BT020635
GenPept AAI22699 AAX08652
RNA Seq Atlas 504301

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca