Bos taurus Gene: BT.52156
Summary
InnateDB Gene IDBG-640875.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.52156
Gene Name proline-rich AKT1 substrate 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000005763
Encoded Proteins
proline-rich AKT1 substrate 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000204673:
AKT1S1 is a proline-rich substrate of AKT (MIM 164730) that binds 14-3-3 protein (see YWHAH, MIM 113508) when phosphorylated (Kovacina et al., 2003 [PubMed 12524439]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:56672752-56680246
Strand Reverse strand
Band
Transcripts
ENSBTAT00000007575 ENSBTAP00000007575
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
Predicted by orthology
Total 17 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006469 negative regulation of protein kinase activity
GO:0032007 negative regulation of TOR signaling
GO:0043523 regulation of neuron apoptotic process
GO:0045792 negative regulation of cell size
GO:0048011 neurotrophin TRK receptor signaling pathway
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0031931 TORC1 complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
TSH pathway
REACTOME
AKT phosphorylates targets in the cytosol pathway
PIP3 activates AKT signaling pathway
DAP12 signaling pathway
DAP12 interactions pathway
PI3K/AKT activation pathway
GAB1 signalosome pathway
Signaling by EGFR pathway
PI3K events in ERBB4 signaling pathway
Signaling by ERBB4 pathway
PI3K events in ERBB2 signaling pathway
Signaling by ERBB2 pathway
PI-3K cascade pathway
Signaling by FGFR pathway
Signaling by SCF-KIT pathway
Downstream signal transduction pathway
Signaling by PDGF pathway
Constitutive PI3K/AKT Signaling in Cancer pathway
Signaling by FGFR in disease pathway
Cellular responses to stress pathway
Signalling by NGF pathway
Signaling by EGFR in Cancer pathway
Downstream signaling of activated FGFR pathway
Role of LAT2/NTAL/LAB on calcium mobilization pathway
Innate Immune System pathway
Fc epsilon receptor (FCERI) signaling pathway
Signal Transduction pathway
Adaptive Immune System pathway
Immune System pathway
HSF1-dependent transactivation pathway
NGF signalling via TRKA from the plasma membrane pathway
Cellular response to heat stress pathway
PI3K/AKT Signaling in Cancer pathway
Signaling by the B Cell Receptor (BCR) pathway
Downstream signaling events of B Cell Receptor (BCR) pathway
Disease pathway
Innate Immune System pathway
Signaling by the B Cell Receptor (BCR) pathway
Signaling by ERBB2 pathway
PI3K/AKT activation pathway
Disease pathway
Cellular responses to stress pathway
Signaling by FGFR in disease pathway
Signaling by ERBB4 pathway
Signaling by SCF-KIT pathway
PIP3 activates AKT signaling pathway
Immune System pathway
Downstream signal transduction pathway
Downstream signaling of activated FGFR pathway
Constitutive PI3K/AKT Signaling in Cancer pathway
HSF1-dependent transactivation pathway
PI3K events in ERBB4 signaling pathway
PI-3K cascade pathway
Signaling by EGFR pathway
Cellular response to heat stress pathway
Role of LAT2/NTAL/LAB on calcium mobilization pathway
Fc epsilon receptor (FCERI) signaling pathway
PI3K/AKT Signaling in Cancer pathway
Signalling by NGF pathway
Adaptive Immune System pathway
Signaling by PDGF pathway
GAB1 signalosome pathway
AKT phosphorylates targets in the cytosol pathway
NGF signalling via TRKA from the plasma membrane pathway
PI3K events in ERBB2 signaling pathway
Signal Transduction pathway
Signaling by FGFR pathway
Signaling by EGFR in Cancer pathway
Downstream signaling events of B Cell Receptor (BCR) pathway
DAP12 interactions pathway
DAP12 signaling pathway
KEGG
mTOR signaling pathway pathway
mTOR signaling pathway pathway
INOH
Insulin receptor signaling pathway
Insulin receptor signaling pathway
PID NCI
Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
mTOR signaling pathway
LKB1 signaling events
Cross-References
SwissProt
TrEMBL F1N197
UniProt Splice Variant
Entrez Gene 514859
UniGene Bt.52156
RefSeq NM_001083434 XM_005219259 XM_005219260 XM_005219261 XM_005219262 XM_005219263
HUGO HGNC:28426
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02047486
GenPept
RNA Seq Atlas 514859