Version 5.4
Bos taurus Gene: RHBDL2
Summary
InnateDB Gene IDBG-641021.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RHBDL2
Gene Name rhomboid-related protein 2
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000008023
Encoded Proteins
IDBP-693336
rhomboid-related protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000158315:
The protein encoded by this gene is a member of the rhomboid family of integral membrane proteins. This family contains proteins that are related to Drosophila rhomboid protein. Members of this family are found in both prokaryotes and eukaryotes and are thought to function as intramembrane serine proteases. The encoded protein is thought to release soluble growth factors by proteolytic cleavage of certain membrane-bound substrates, including ephrin B2 and ephrin B3. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:107634942-107692934
Strand Forward strand
Band
Transcripts
ENSBTAT00000056623 ENSBTAP00000052684
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000158315
View Gene Order
ENSMUSG00000043333
View Gene Order
Cross-References
SwissProt
TrEMBL A6QPK1
UniProt Splice Variant
Entrez Gene 514943
UniGene Bt.2986
RefSeq NM_001102014 XM_005204729
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC149360 DAAA02009155
GenPept AAI49361
RNA Seq Atlas 514943

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca