Version 5.4
Bos taurus Gene: LGALS3
Summary
InnateDB Gene IDBG-641390.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LGALS3
Gene Name galectin-2
Synonyms LGALS3
Species Bos taurus
Ensembl Gene ENSBTAG00000021615
Encoded Proteins
IDBP-693752
galectin-2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
PMID 15356130
[Homo sapiens] LGASL2 binds to T cells in a beta-galactoside-specific manner and acts as pro-apoptotic effector for activated T cells.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000100079:
The protein encoded by this gene is a soluble beta-galactoside binding lectin. The encoded protein is found as a homodimer and can bind to lymphotoxin-alpha. A single nucleotide polymorphism in an intron of this gene can alter the transcriptional level of the protein, with a resultant increased risk of myocardial infarction. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:109933973-109940236
Strand Reverse strand
Band
Transcripts
ENSBTAT00000028802 ENSBTAP00000028802
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0030246 carbohydrate binding
Biological Process
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000100079
View Gene Order
ENSMUSG00000043501
View Gene Order
Cross-References
SwissProt
TrEMBL Q0VBW6
UniProt Splice Variant
Entrez Gene 511098
UniGene Bt.28067
RefSeq NM_001075494 XM_005207321
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC120473 DAAA02014630
GenPept AAI20474
RNA Seq Atlas 511098

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca