Version 5.4
Bos taurus Gene: BT.54136
Summary
InnateDB Gene IDBG-641513.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.54136
Gene Name beta-defensin 123 precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000020555
Encoded Proteins
IDBP-693886
beta-defensin 123
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000180424:
Defensins are cysteine-rich cationic polypeptides that are important in the host immunologic response to invading microorganisms. The protein encoded by this gene is secreted and is a member of the beta defensin protein family. Beta defensin genes are found in several clusters throughout the genome, with this gene mapping to a cluster at 20q11.1. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:61584391-61595672
Strand Forward strand
Band
Transcripts
ENSBTAT00000027390 ENSBTAP00000027390
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006952 defense response
GO:0042742 defense response to bacterium
Cellular Component
GO:0005576 extracellular region
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000180424
View Gene Order
ENSMUSG00000044863
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_115897
Beta defensins pathway
REACT_115846
Defensins pathway
REACT_6802
Innate Immune System pathway
REACT_6900
Immune System pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F6RSW1
UniProt Splice Variant
Entrez Gene 786992
UniGene Bt.54136
RefSeq NM_001102343
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02036381 DAAA02036382
GenPept
RNA Seq Atlas 786992

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca