Version 5.4
Bos taurus Gene: MRPS2
Summary
InnateDB Gene IDBG-641574.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MRPS2
Gene Name 28S ribosomal protein S2, mitochondrial
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000005688
Encoded Proteins
IDBP-693950
28S ribosomal protein S2, mitochondrial
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000122140:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S2 family. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:106447320-106450536
Strand Reverse strand
Band
Transcripts
ENSBTAT00000007473 ENSBTAP00000007473
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005622 intracellular
GO:0005739 mitochondrion
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0030529 ribonucleoprotein complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000122140
View Gene Order
ENSMUSG00000035772
View Gene Order
Pathways
NETPATH
REACTOME
REACT_270797
Mitochondrial translation initiation pathway
REACT_271447
Mitochondrial translation elongation pathway
REACT_270450
Mitochondrial translation pathway
REACT_219259
Organelle biogenesis and maintenance pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa03010
Ribosome pathway
mmu03010
Ribosome pathway
INOH
PID NCI
Cross-References
SwissProt P82923
TrEMBL
UniProt Splice Variant
Entrez Gene 505681
UniGene Bt.28838
RefSeq NM_001098877
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC146028
GenPept AAI46029
RNA Seq Atlas 505681

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca