Version 5.4
Homo sapiens Gene: DHX37
Summary
InnateDB Gene IDBG-64213.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DHX37
Gene Name DEAH (Asp-Glu-Ala-His) box polypeptide 37
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000150990
Encoded Proteins
IDBP-64215
DEAH (Asp-Glu-Ala-His) box polypeptide 37
IDBP-583174
DEAH (Asp-Glu-Ala-His) box polypeptide 37
IDBP-588457
DEAH (Asp-Glu-Ala-His) box polypeptide 37
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a DEAD box protein. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:124946825-124989122
Strand Reverse strand
Band q24.31
Transcripts
ENST00000308736 ENSP00000311135
ENST00000507267
ENST00000542400
ENST00000539298
ENST00000544745 ENSP00000439009
ENST00000543962 ENSP00000443661
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0004386 helicase activity
GO:0005524 ATP binding
Biological Process
GO:0006810 transport
GO:0008152 metabolic process
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000029480
View Gene Order
ENSBTAG00000020414
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.107382
RefSeq NM_032656 XM_005253590
HUGO
OMIM
CCDS CCDS9261
HPRD 10883
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca