Version 5.4
Bos taurus Gene: RAB3GAP1
Summary
InnateDB Gene IDBG-642255.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RAB3GAP1
Gene Name rab3 GTPase-activating protein catalytic subunit
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000013449
Encoded Proteins
IDBP-694698
rab3 GTPase-activating protein catalytic subunit
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000115839:
This gene encodes the catalytic subunit of a Rab GTPase activating protein. The encoded protein forms a heterodimer with a non-catalytic subunit to specifically regulate the activity of members of the Rab3 subfamily of small G proteins. This protein mediates the hydrolysis of GTP bound Rab3 to the GDP bound form. Mutations in this gene are associated with Warburg micro syndrome. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:62457398-62568130
Strand Reverse strand
Band
Transcripts
ENSBTAT00000017891 ENSBTAP00000017891
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005097 Rab GTPase activator activity
GO:0017137 Rab GTPase binding
Biological Process
GO:0007420 brain development
GO:0021854 hypothalamus development
GO:0032851 positive regulation of Rab GTPase activity
GO:0034389 lipid particle organization
GO:0043010 camera-type eye development
GO:0043087 regulation of GTPase activity
GO:0060325 face morphogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000115839
View Gene Order
ENSMUSG00000036104
View Gene Order
Cross-References
SwissProt
TrEMBL A4FUE5
UniProt Splice Variant
Entrez Gene 535393
UniGene Bt.66644 Bt.6988
RefSeq NM_001083483 XM_005202535
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC114755 DAAA02005002 DAAA02005003
GenPept AAI14756
RNA Seq Atlas 535393

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca