Version 5.4
| Bos taurus Gene: EP1 | |||||||||||
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| Summary | |||||||||||
| InnateDB Gene | IDBG-642675.3 | ||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
| Gene Symbol | EP1 | ||||||||||
| Gene Name | prostaglandin E2 receptor EP1 subtype | ||||||||||
| Synonyms | EP1 | ||||||||||
| Species | Bos taurus | ||||||||||
| Ensembl Gene | ENSBTAG00000017041 | ||||||||||
| Encoded Proteins |
Prostaglandin E2 receptor EP1
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| Protein Structure | |||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
| Entrez Gene | |||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000160951:
The protein encoded by this gene is a member of the G protein-coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). Through a phosphatidylinositol-calcium second messenger system, G-Q proteins mediate this receptor's activity. Knockout studies in mice suggested a role of this receptor in mediating algesia and in regulation of blood pressure. Studies in mice also suggested that this gene may mediate adrenocorticotropic hormone response to bacterial endotoxin. [provided by RefSeq, Jul 2008] The protein encoded by this gene is a member of the G protein-coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). Through a phosphatidylinositol-calcium second messenger system, G-Q proteins mediate this receptor\'s activity. Knockout studies in mice suggested a role of this receptor in mediating algesia and in regulation of blood pressure. Studies in mice also suggested that this gene may mediate adrenocorticotropic hormone response to bacterial endotoxin. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||
| Type | Protein coding | ||||||||||
| Genomic Location | Chromosome 7:12399523-12401644 | ||||||||||
| Strand | Forward strand | ||||||||||
| Band | |||||||||||
| Transcripts |
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| Interactions | |||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||||||
| NETPATH | |||||||||||
| REACTOME |
G alpha (q) signalling events pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
Prostanoid ligand receptors pathway
Eicosanoid ligand-binding receptors pathway
Class A/1 (Rhodopsin-like receptors) pathway
Signaling by GPCR pathway
Signal Transduction pathway
GPCR downstream signaling pathway
GPCR ligand binding pathway
GPCR downstream signaling pathway
Prostanoid ligand receptors pathway
Signaling by GPCR pathway
Class A/1 (Rhodopsin-like receptors) pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
GPCR ligand binding pathway
G alpha (q) signalling events pathway
Signal Transduction pathway
Eicosanoid ligand-binding receptors pathway
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| KEGG |
Neuroactive ligand-receptor interaction pathway
Calcium signaling pathway pathway
Calcium signaling pathway pathway
Neuroactive ligand-receptor interaction pathway
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| INOH | |||||||||||
| PID NCI | |||||||||||
| Cross-References | |||||||||||
| SwissProt | |||||||||||
| TrEMBL | F1MUY4 Q95M52 | ||||||||||
| UniProt Splice Variant | |||||||||||
| Entrez Gene | 507437 | ||||||||||
| UniGene | Bt.106423 | ||||||||||
| RefSeq | NM_001192148 XM_005208604 | ||||||||||
| HUGO | |||||||||||
| OMIM | |||||||||||
| CCDS | |||||||||||
| HPRD | |||||||||||
| IMGT | |||||||||||
| EMBL | AJ295563 DAAA02019334 | ||||||||||
| GenPept | CAC44528 | ||||||||||
| RNA Seq Atlas | 507437 | ||||||||||