InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: SCO2

Summary

InnateDB Gene

IDBG-642754.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SCO2

Gene Name

Protein SCO2 homolog, mitochondrial

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000012609

Encoded Proteins

IDBP-695245

Protein SCO2 homolog, mitochondrial

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000130489:
Cytochrome c oxidase (COX) catalyzes the transfer of electrons from cytochrome c to molecular oxygen, which helps to maintain the proton gradient across the inner mitochondrial membrane that is necessary for aerobic ATP production. Human COX is a multimeric protein complex that requires several assembly factors; this gene encodes one of the COX asembly factors. The encoded protein is a metallochaperone that is involved in the biogenesis of cytochrome c oxidase subunit II. Mutations in this gene are associated with fatal infantile encephalocardiomyopathy. [provided by RefSeq, Dec 2009]
Cytochrome c oxidase (COX) catalyzes the transfer of electrons from cytochrome c to molecular oxygen, which helps to maintain the proton gradient across the inner mitochondrial membrane that is necessary for aerobic ATP production. Human COX is a multimeric protein complex that requires several assembly factors; this gene encodes one of the COX assembly factors. The encoded protein is a metallochaperone that is involved in the biogenesis of cytochrome c oxidase subunit II. Mutations in this gene are associated with fatal infantile encephalocardiomyopathy. [provided by RefSeq, May 2014]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 5:120032226-120034043

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000016742

ENSBTAP00000016742

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 26 interaction(s) predicted by orthology.

Predicted by orthology
Total	26 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005507	copper ion binding
GO:0016209	antioxidant activity
GO:0016491	oxidoreductase activity
GO:0046872	metal ion binding

Biological Process

GO:0001654	eye development
GO:0001701	in utero embryonic development
GO:0003012	muscle system process
GO:0006825	copper ion transport
GO:0006878	cellular copper ion homeostasis
GO:0008535	respiratory chain complex IV assembly
GO:0014823	response to activity
GO:0022904	respiratory electron transport chain
GO:0055070	copper ion homeostasis
GO:0055114	oxidation-reduction process