Version 5.4
Bos taurus Gene: FOXJ1
Summary
InnateDB Gene IDBG-643101.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FOXJ1
Gene Name forkhead box protein J1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000007916
Encoded Proteins
IDBP-695628
forkhead box J1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000129654:
This gene encodes a member of the forkhead family of transcription factors. Similar genes in zebrafish and mouse have been shown to regulate the transcription of genes that control the production of motile cilia. The mouse ortholog also functions in the determination of left-right asymmetry. Polymorphisms in this gene are associated with systemic lupus erythematosus and allergic rhinitis.[provided by RefSeq, Sep 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:56171932-56175103
Strand Forward strand
Band
Transcripts
ENSBTAT00000010408 ENSBTAP00000010408
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000976 transcription regulatory region sequence-specific DNA binding
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0002508 central tolerance induction
GO:0002635 negative regulation of germinal center formation
GO:0002897 positive regulation of central B cell tolerance induction
GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006366 transcription from RNA polymerase II promoter
GO:0006959 humoral immune response
GO:0007420 brain development
GO:0030036 actin cytoskeleton organization
GO:0030856 regulation of epithelial cell differentiation
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0032862 activation of Rho GTPase activity
GO:0033085 negative regulation of T cell differentiation in thymus
GO:0035089 establishment of apical/basal cell polarity
GO:0035502 metanephric part of ureteric bud development
GO:0042130 negative regulation of T cell proliferation
GO:0042384 cilium assembly
GO:0045409 negative regulation of interleukin-6 biosynthetic process
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0050869 negative regulation of B cell activation
GO:0050900 leukocyte migration
GO:0060271 cilium morphogenesis
GO:0060429 epithelium development
GO:0060972 left/right pattern formation
GO:0072016 glomerular parietal epithelial cell development
GO:1901248 positive regulation of lung ciliated cell differentiation
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000129654
View Gene Order
ENSMUSG00000034227
View Gene Order
Cross-References
SwissProt
TrEMBL E1BNF3
UniProt Splice Variant
Entrez Gene 505891
UniGene Bt.88381
RefSeq NM_001192076 XM_005221165
HUGO HGNC:3816
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02049505
GenPept
RNA Seq Atlas 505891

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca