Bos taurus Gene: CXCL9
Summary
InnateDB Gene IDBG-643104.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CXCL9
Gene Name C-X-C motif chemokine 9
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000038639
Encoded Proteins
C-X-C motif chemokine 9
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
[Homo sapiens] CXCL9 exert direct antimicrobial effects in vitro against Bacillus anthracis spore and bacilli in a receptor-independent manner and contributes to pulmonary innate immunity. (Demonstrated in murine model)
[Mus musculus] Cxcl9 exert direct antimicrobial effects in vitro against Bacillus anthracis spores and bacilli in a receptor-independent manner and contributes to pulmonary innate immunity.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000138755:
The function of this gene has not been specifically defined; however, it is thought to be involved in T cell trafficking. This gene has been localized to 4q21 with INP10, which is also a member of the chemokine family of cytokines. [provided by RefSeq, Jul 2008]
This antimicrobial gene encodes a protein thought to be involved in T cell trafficking. The encoded protein binds to C-X-C motif chemokine 3 and is a chemoattractant for lymphocytes but not for neutrophils. [provided by RefSeq, Sep 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:92600177-92604818
Strand Reverse strand
Band
Transcripts
ENSBTAT00000002257 ENSBTAP00000002257
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005125 cytokine activity
GO:0005515 protein binding
GO:0008009 chemokine activity
GO:0048248 CXCR3 chemokine receptor binding
Biological Process
GO:0006935 chemotaxis
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0030816 positive regulation of cAMP metabolic process
GO:0042127 regulation of cell proliferation
GO:0043950 positive regulation of cAMP-mediated signaling
GO:0051281 positive regulation of release of sequestered calcium ion into cytosol
GO:0051607 defense response to virus
GO:0060326 cell chemotaxis
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0009897 external side of plasma membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathways
NETPATH
REACTOME
Peptide ligand-binding receptors pathway
Signaling by GPCR pathway
G alpha (i) signalling events pathway
Signal Transduction pathway
GPCR downstream signaling pathway
GPCR ligand binding pathway
Class A/1 (Rhodopsin-like receptors) pathway
Chemokine receptors bind chemokines pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
G alpha (i) signalling events pathway
Chemokine receptors bind chemokines pathway
Peptide ligand-binding receptors pathway
Class A/1 (Rhodopsin-like receptors) pathway
Signaling by GPCR pathway
Signal Transduction pathway
GPCR downstream signaling pathway
GPCR ligand binding pathway
GPCR downstream signaling pathway
Signaling by GPCR pathway
Class A/1 (Rhodopsin-like receptors) pathway
GPCR ligand binding pathway
Peptide ligand-binding receptors pathway
G alpha (i) signalling events pathway
Chemokine receptors bind chemokines pathway
Signal Transduction pathway
KEGG
Cytokine-cytokine receptor interaction pathway
Toll-like receptor signaling pathway pathway
Chemokine signaling pathway pathway
Cytokine-cytokine receptor interaction pathway
Toll-like receptor signaling pathway pathway
Chemokine signaling pathway pathway
INOH
PID NCI
IL23-mediated signaling events
CXCR3-mediated signaling events
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001113172
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas
Transcript Frequencies
Tag Count based mRNA-Abundances across 87 different Tissues (TPM).

Based on Data from Bovine Gene Atlas

Tag Count based mRNA-Abundances across 87 different Tissues (TPM)

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