InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: HNRNPD

Summary

InnateDB Gene

IDBG-643180.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HNRNPD

Gene Name

heterogeneous nuclear ribonucleoprotein D0

Synonyms

AUF1; HNRPD

Species

Bos taurus

Ensembl Gene

ENSBTAG00000013952

Encoded Proteins

IDBP-695721

heterogeneous nuclear ribonucleoprotein D0

IDBP-695724

heterogeneous nuclear ribonucleoprotein D0

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000138668:
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 6:98916663-98933842

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000056365	ENSBTAP00000049251
ENSBTAT00000018540	ENSBTAP00000018540

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 111 interaction(s) predicted by orthology.

Predicted by orthology
Total	111 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0005515	protein binding
GO:0042162	telomeric DNA binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0042752	regulation of circadian rhythm
GO:0043488	regulation of mRNA stability
GO:0045727	positive regulation of translation
GO:0097167	circadian regulation of translation