Version 5.4
| Bos taurus Gene: S1PR5 | |||||||
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| Summary | |||||||
| InnateDB Gene | IDBG-643290.3 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | S1PR5 | ||||||
| Gene Name | sphingosine 1-phosphate receptor 5 | ||||||
| Synonyms | EDG8 | ||||||
| Species | Bos taurus | ||||||
| Ensembl Gene | ENSBTAG00000003544 | ||||||
| Encoded Proteins |
sphingosine-1-phosphate receptor 5
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| Protein Structure | |||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||
| Entrez Gene | |||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000180739:
The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1; MIM 601974) are S1P receptors; others (e.g., EDG2; MIM 602282) are LPA receptors.[supplied by OMIM, Mar 2008] |
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| Gene Information | |||||||
| Type | Protein coding | ||||||
| Genomic Location | Chromosome 7:16248165-16252264 | ||||||
| Strand | Reverse strand | ||||||
| Band | |||||||
| Transcripts |
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| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||
| NETPATH | |||||||
| REACTOME |
G alpha (i) signalling events pathway
Lysosphingolipid and LPA receptors pathway
Class A/1 (Rhodopsin-like receptors) pathway
Signaling by GPCR pathway
Signal Transduction pathway
GPCR downstream signaling pathway
GPCR ligand binding pathway
GPCR downstream signaling pathway
Signaling by GPCR pathway
Class A/1 (Rhodopsin-like receptors) pathway
GPCR ligand binding pathway
G alpha (i) signalling events pathway
Lysosphingolipid and LPA receptors pathway
Signal Transduction pathway
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| KEGG |
Neuroactive ligand-receptor interaction pathway
Neuroactive ligand-receptor interaction pathway
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| INOH | |||||||
| PID NCI |
Sphingosine 1-phosphate (S1P) pathway
S1P5 pathway
S1P4 pathway
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| Cross-References | |||||||
| SwissProt | |||||||
| TrEMBL | F1MV28 | ||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 517533 | ||||||
| UniGene | Bt.69747 | ||||||
| RefSeq | NM_001192475 XM_005208750 XM_005208751 | ||||||
| HUGO | HGNC:14299 | ||||||
| OMIM | |||||||
| CCDS | |||||||
| HPRD | |||||||
| IMGT | |||||||
| EMBL | DAAA02019465 | ||||||
| GenPept | |||||||
| RNA Seq Atlas | 517533 | ||||||