Version 5.4
Bos taurus Gene: BT.25759
Summary
InnateDB Gene IDBG-643618.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.25759
Gene Name zinc transporter ZIP6
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000000998
Encoded Proteins
IDBP-696181
zinc transporter ZIP6
IDBP-696184
zinc transporter ZIP6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000141424:
Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A6 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 24:21317313-21337841
Strand Forward strand
Band
Transcripts
ENSBTAT00000065246 ENSBTAP00000054598
ENSBTAT00000001322 ENSBTAP00000001322
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005385 zinc ion transmembrane transporter activity
GO:0046873 metal ion transmembrane transporter activity
Biological Process
GO:0006882 cellular zinc ion homeostasis
GO:0030001 metal ion transport
GO:0055085 transmembrane transport
GO:0071577 zinc ion transmembrane transport
GO:0071578 zinc ion transmembrane import
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0031258 lamellipodium membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000141424
View Gene Order
ENSMUSG00000024270
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_20603
Zinc influx into cells by the SLC39 gene family pathway
REACT_20547
Metal ion SLC transporters pathway
REACT_19305
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_20530
Zinc transporters pathway
REACT_19118
SLC-mediated transmembrane transport pathway
REACT_217615
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
REACT_247550
SLC-mediated transmembrane transport pathway
REACT_198240
Zinc influx into cells by the SLC39 gene family pathway
REACT_243781
Zinc transporters pathway
REACT_253400
Transmembrane transport of small molecules pathway
REACT_251299
Metal ion SLC transporters pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E1B8W8
UniProt Splice Variant
Entrez Gene 524456
UniGene Bt.25759
RefSeq XM_005223983 XM_005223984 XM_005223985 NM_001144092
HUGO HGNC:18607
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02056390
GenPept
RNA Seq Atlas 524456

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca