Version 5.4
| Bos taurus Gene: LAMA3 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-643892.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | LAMA3 | ||||||||
| Gene Name | Uncharacterized protein | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Gene | ENSBTAG00000027181 | ||||||||
| Encoded Proteins |
laminin, alpha 3
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000053747:
Laminins are basement membrane components thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. The protein encoded by this gene is the alpha-3 subunit of laminin 5, which is a complex glycoprotein composed of three subunits (alpha, beta, and gamma). Laminin 5 is thought to be involved in cell adhesion, signal transduction and differentiation of keratinocytes. Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis bullosa. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 24:33072942-33324798 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | |||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH |
Alpha6Beta4Integrin pathway
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| REACTOME |
Anchoring fibril formation pathway
Assembly of collagen fibrils and other multimeric structures pathway
Type I hemidesmosome assembly pathway
Cell-Cell communication pathway
Extracellular matrix organization pathway
Cell junction organization pathway
Degradation of the extracellular matrix pathway
ECM proteoglycans pathway
Non-integrin membrane-ECM interactions pathway
Laminin interactions pathway
Collagen formation pathway
Extracellular matrix organization pathway
Laminin interactions pathway
Non-integrin membrane-ECM interactions pathway
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| KEGG |
ECM-receptor interaction pathway
Small cell lung cancer pathway
Focal adhesion pathway
Pathways in cancer pathway
Amoebiasis pathway
Toxoplasmosis pathway
ECM-receptor interaction pathway
Small cell lung cancer pathway
Focal adhesion pathway
Pathways in cancer pathway
Amoebiasis pathway
Toxoplasmosis pathway
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| INOH | |||||||||
| PID NCI |
Syndecan-2-mediated signaling events
Beta1 integrin cell surface interactions
Validated transcriptional targets of AP1 family members Fra1 and Fra2
Alpha6 beta4 integrin-ligand interactions
Syndecan-4-mediated signaling events
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| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | F1MDD5 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 100336873 | ||||||||
| UniGene | Bt.111796 Bt.12589 | ||||||||
| RefSeq | XM_003587770 XM_005200277 | ||||||||
| HUGO | HGNC:6483 | ||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | DAAA02056591 DAAA02056592 DAAA02056593 DAAA02056594 DAAA02056595 DAAA02056596 DAAA02056597 DAAA02056598 DAAA02056599 DAAA02056600 DAAA02056601 DAAA02056602 | ||||||||
| GenPept | |||||||||
| RNA Seq Atlas | 100336873 | ||||||||