Bos taurus Gene: COL4A4
|Last Modified||2013-04-25 [Report errors or provide feedback]|
|Gene Name||Collagen alpha-4(IV) chain|
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000081052:
This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. This particular collagen IV subunit, however, is only found in a subset of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Mutations in this gene are associated with type II autosomal recessive Alport syndrome (hereditary glomerulonephropathy) and with familial benign hematuria (thin basement membrane disease). Two transcripts, differing only in their transcription start sites, have been identified for this gene and, as is common for collagen genes, multiple polyadenylation sites are found in the 3' UTR. [provided by RefSeq, Jul 2008]
|Genomic Location||Chromosome 2: 115971118-116104632|
|Number of Interactions||
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
|Pathway Predictions based on Human Orthology Data|
|UniProt Splice Variant|
|EMBL||DAAA02006104 DAAA02006105 DAAA02006106 DAAA02006107 DAAA02006108 DAAA02006109 DAAA02006110 DAAA02006111 DAAA02006112|
|RNA Seq Atlas||407107|