Version 5.4
Bos taurus Gene: BT.74375
Summary
InnateDB Gene IDBG-644376.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.74375
Gene Name Golgi reassembly-stacking protein 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000047135
Encoded Proteins
IDBP-697014
golgi reassembly stacking protein 1, 65kDa
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000114745:
The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a membrane protein involved in establishing the stacked structure of the Golgi apparatus. It is a caspase-3 substrate, and cleavage of this encoded protein contributes to Golgi fragmentation in apoptosis. This encoded protein can form a complex with the Golgi matrix protein GOLGA2, and this complex binds to the vesicle docking protein p115. Several alternatively spliced transcript variants of this gene have been identified, but their full-length natures have not been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:12471342-12480021
Strand Reverse strand
Band
Transcripts
ENSBTAT00000065507 ENSBTAP00000055527
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0050774 negative regulation of dendrite morphogenesis
Cellular Component
GO:0005794 Golgi apparatus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000114745
View Gene Order
ENSMUSG00000032513
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_1100
Golgi Cisternae Pericentriolar Stack Reorganization pathway
REACT_115566
Cell Cycle pathway
REACT_910
M Phase pathway
REACT_765
Mitotic Prophase pathway
REACT_152
Cell Cycle, Mitotic pathway
REACT_249770
Cell Cycle, Mitotic pathway
REACT_188804
Cell Cycle pathway
REACT_241408
M Phase pathway
REACT_257344
Golgi Cisternae Pericentriolar Stack Reorganization pathway
REACT_250557
Mitotic Prophase pathway
KEGG
INOH
PID NCI
plk1_pathway
PLK1 signaling events
Cross-References
SwissProt
TrEMBL G3N105
UniProt Splice Variant
Entrez Gene 613757
UniGene Bt.74375
RefSeq NM_001046518
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02053662
GenPept
RNA Seq Atlas 613757
Transcript Frequencies
Tag Count based mRNA-Abundances across 87 different Tissues (TPM).

Based on Data from Bovine Gene Atlas

Tag Count based mRNA-Abundances across 87 different Tissues (TPM)

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If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca