Version 5.4
Bos taurus Gene: BT.102977
Summary
InnateDB Gene IDBG-644397.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.102977
Gene Name cysteine/serine-rich nuclear protein 1
Synonyms AXUD1
Species Bos taurus
Ensembl Gene ENSBTAG00000003845
Encoded Proteins
IDBP-697032
cysteine/serine-rich nuclear protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000144655:
This gene encodes a protein that localizes to the nucleus and expression of this gene is induced in response to elevated levels of axin. The Wnt signalling pathway, which is negatively regulated by axin, is important in axis formation in early development and impaired regulation of this signalling pathway is often involved in tumors. A decreased level of expression of this gene in tumors compared to the level of expression in their corresponding normal tissues suggests that this gene product has a tumor suppressor function. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:12520393-12532806
Strand Reverse strand
Band
Transcripts
ENSBTAT00000005016 ENSBTAP00000005016
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001228 RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0009791 post-embryonic development
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048008 platelet-derived growth factor receptor signaling pathway
GO:0048705 skeletal system morphogenesis
GO:0060021 palate development
GO:0060325 face morphogenesis
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000144655
View Gene Order
ENSMUSG00000032515
View Gene Order
Cross-References
SwissProt
TrEMBL F1MDN9
UniProt Splice Variant
Entrez Gene 515406
UniGene Bt.102977
RefSeq NM_001098035 XM_005222458 XM_005222459
HUGO HGNC:14300
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02053666
GenPept
RNA Seq Atlas 515406

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca