Version 5.4
Bos taurus Gene: CCS
Summary
InnateDB Gene IDBG-644464.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CCS
Gene Name copper chaperone for superoxide dismutase
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000004343
Encoded Proteins
IDBP-697178
copper chaperone for superoxide dismutase
IDBP-697199
copper chaperone for superoxide dismutase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000173992:
Copper chaperone for superoxide dismutase specifically delivers Cu to copper/zinc superoxide dismutase and may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 29:45274394-45288010
Strand Forward strand
Band
Transcripts
ENSBTAT00000044928 ENSBTAP00000042370
ENSBTAT00000005683 ENSBTAP00000005683
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004784 superoxide dismutase activity
GO:0005507 copper ion binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006801 superoxide metabolic process
GO:0019430 removal of superoxide radicals
GO:0030001 metal ion transport
GO:0051353 positive regulation of oxidoreductase activity
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000173992
View Gene Order
ENSMUSG00000034108
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_120956
Cellular responses to stress pathway
REACT_172715
Detoxification of Reactive Oxygen Species pathway
REACT_188957
Cellular responses to stress pathway
REACT_189141
Detoxification of Reactive Oxygen Species pathway
KEGG
hsa05014
Amyotrophic lateral sclerosis (ALS) pathway
mmu05014
Amyotrophic lateral sclerosis (ALS) pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL Q2KHY4
UniProt Splice Variant
Entrez Gene 515022
UniGene Bt.53065
RefSeq NM_001046187 XM_005227076
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC112838 DAAA02063594
GenPept AAI12839
RNA Seq Atlas 515022

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca