Bos taurus Gene: CHRND
Summary
InnateDB Gene IDBG-644498.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CHRND
Gene Name Acetylcholine receptor subunit delta
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000011390
Encoded Proteins
Acetylcholine receptor subunit delta
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000135902:
The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Defects in this gene are a cause of multiple pterygium syndrome lethal type (MUPSL), congenital myasthenic syndrome slow-channel type (SCCMS), and congenital myasthenic syndrome fast-channel type (FCCMS). Several transcript variants, some protein-coding and some not, have been found for this gene. [provided by RefSeq, Feb 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:120975092-120982350
Strand Forward strand
Band
Transcripts
ENSBTAT00000015135 ENSBTAP00000015135
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004889 acetylcholine-activated cation-selective channel activity
GO:0005216 ion channel activity
GO:0005230 extracellular ligand-gated ion channel activity
GO:0005515 protein binding
GO:0042166 acetylcholine binding
Biological Process
GO:0006810 transport
GO:0006811 ion transport
GO:0006812 cation transport
GO:0034220 ion transmembrane transport
GO:0042391 regulation of membrane potential
GO:0048630 skeletal muscle tissue growth
GO:0050881 musculoskeletal movement
Cellular Component
GO:0005886 plasma membrane
GO:0005892 acetylcholine-gated channel complex
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030054 cell junction
GO:0045202 synapse
GO:0045211 postsynaptic membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathways
NETPATH
REACTOME
Presynaptic nicotinic acetylcholine receptors pathway
Transmission across Chemical Synapses pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
Highly sodium permeable acetylcholine nicotinic receptors pathway
Neuronal System pathway
Activation of Nicotinic Acetylcholine Receptors pathway
Postsynaptic nicotinic acetylcholine receptors pathway
Acetylcholine Binding And Downstream Events pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Neuronal System pathway
Postsynaptic nicotinic acetylcholine receptors pathway
Highly sodium permeable acetylcholine nicotinic receptors pathway
Activation of Nicotinic Acetylcholine Receptors pathway
Presynaptic nicotinic acetylcholine receptors pathway
Transmission across Chemical Synapses pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
Acetylcholine Binding And Downstream Events pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
Presynaptic nicotinic acetylcholine receptors pathway
Highly sodium permeable acetylcholine nicotinic receptors pathway
Neuronal System pathway
Activation of Nicotinic Acetylcholine Receptors pathway
Acetylcholine Binding And Downstream Events pathway
Postsynaptic nicotinic acetylcholine receptors pathway
Transmission across Chemical Synapses pathway
KEGG
Neuroactive ligand-receptor interaction pathway
Neuroactive ligand-receptor interaction pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.89
RefSeq NM_174271
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas