Version 5.4
Bos taurus Gene: CORO1B
Summary
InnateDB Gene IDBG-644733.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CORO1B
Gene Name coronin-1B
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000004783
Encoded Proteins
IDBP-697395
coronin, actin binding protein, 1B
IDBP-697396
coronin, actin binding protein, 1B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000172725:
Members of the coronin family, such as CORO1B, are WD repeat-containing actin-binding proteins that regulate cell motility (Cai et al., 2005 [PubMed 16027158]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 29:45974636-45980142
Strand Reverse strand
Band
Transcripts
ENSBTAT00000029972 ENSBTAP00000029960
ENSBTAT00000006281 ENSBTAP00000006281
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0042802 identical protein binding
GO:0051015 actin filament binding
GO:0071933 Arp2/3 complex binding
Biological Process
GO:0016477 cell migration
GO:0030036 actin cytoskeleton organization
GO:0031529 ruffle organization
GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation
GO:0035767 endothelial cell chemotaxis
GO:0042060 wound healing
GO:0051017 actin filament bundle assembly
GO:0090135 actin filament branching
GO:1902463 protein localization to cell leading edge
GO:2000394 positive regulation of lamellipodium morphogenesis
Cellular Component
GO:0001725 stress fiber
GO:0005737 cytoplasm
GO:0005884 actin filament
GO:0015629 actin cytoskeleton
GO:0030027 lamellipodium
GO:0031252 cell leading edge
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000172725
View Gene Order
ENSMUSG00000024835
View Gene Order
Cross-References
SwissProt
TrEMBL F1MK51 H7BWW0 Q58CZ1
UniProt Splice Variant
Entrez Gene 510128
UniGene Bt.49709
RefSeq NM_001113243
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BT021806 DAAA02063620 DAAA02063621
GenPept AAX46653
RNA Seq Atlas 510128

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca