InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: RDH10

Summary

InnateDB Gene

IDBG-644770.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RDH10

Gene Name

Retinol dehydrogenase 10

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000020143

Encoded Proteins

IDBP-697434

Retinol dehydrogenase 10

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000121039:
This gene encodes a retinol dehydrogenase, which converts all-trans-retinol to all-trans-retinal, with preference for NADP as a cofactor. Studies in mice suggest that this protein is essential for synthesis of embryonic retinoic acid and is required for limb, craniofacial, and organ development. [provided by RefSeq, Dec 2011]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 14:38745909-38775000

Strand

Forward strand

Band

Transcripts

ENSBTAT00000026830

ENSBTAP00000026830

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004745	retinol dehydrogenase activity
GO:0016491	oxidoreductase activity
GO:0052650	NADP-retinol dehydrogenase activity

Biological Process

GO:0001656	metanephros development
GO:0001701	in utero embryonic development
GO:0002138	retinoic acid biosynthetic process
GO:0007601	visual perception
GO:0008152	metabolic process
GO:0008406	gonad development
GO:0009887	organ morphogenesis
GO:0014032	neural crest cell development
GO:0031076	embryonic camera-type eye development
GO:0035115	embryonic forelimb morphogenesis
GO:0042572	retinol metabolic process
GO:0042574	retinal metabolic process
GO:0043583	ear development
GO:0043584	nose development
GO:0048568	embryonic organ development
GO:0048703	embryonic viscerocranium morphogenesis
GO:0055114	oxidation-reduction process
GO:0060431	primary lung bud formation
GO:0060449	bud elongation involved in lung branching

Cellular Component

GO:0005737	cytoplasm
GO:0005783	endoplasmic reticulum
GO:0005789	endoplasmic reticulum membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0031090	organelle membrane
GO:0043231	intracellular membrane-bounded organelle