Version 5.4
Bos taurus Gene: BT.55540
Summary
InnateDB Gene IDBG-644806.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.55540
Gene Name ER degradation-enhancing alpha-mannosidase-like 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000012904
Encoded Proteins
IDBP-697474
ER degradation-enhancing alpha-mannosidase-like 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000134109:
Gene Information
Type Protein coding
Genomic Location Chromosome 22:21268891-21295366
Strand Reverse strand
Band
Transcripts
ENSBTAT00000017152 ENSBTAP00000017152
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0051787 misfolded protein binding
Biological Process
GO:0030433 ER-associated ubiquitin-dependent protein catabolic process
Cellular Component
GO:0016020 membrane
GO:0030176 integral component of endoplasmic reticulum membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000134109
View Gene Order
ENSMUSG00000030104
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_25091
ER Quality Control Compartment (ERQC) pathway
REACT_18273
XBP1(S) activates chaperone genes pathway
REACT_18368
IRE1alpha activates chaperones pathway
REACT_23810
Calnexin/calreticulin cycle pathway
REACT_23878
N-glycan trimming in the ER and Calnexin/Calreticulin cycle pathway
REACT_22426
Asparagine N-linked glycosylation pathway
REACT_18356
Unfolded Protein Response (UPR) pathway
REACT_22161
Post-translational protein modification pathway
REACT_17015
Metabolism of proteins pathway
REACT_239697
Unfolded Protein Response (UPR) pathway
REACT_247926
Metabolism of proteins pathway
REACT_236283
Post-translational protein modification pathway
REACT_231085
IRE1alpha activates chaperones pathway
REACT_237472
Asparagine N-linked glycosylation pathway
REACT_198606
ER Quality Control Compartment (ERQC) pathway
REACT_106572
XBP1(S) activates chaperone genes pathway
REACT_198618
N-glycan trimming in the ER and Calnexin/Calreticulin cycle pathway
REACT_198616
Calnexin/calreticulin cycle pathway
KEGG
hsa04141
Protein processing in endoplasmic reticulum pathway
mmu04141
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1MHH3
UniProt Splice Variant
Entrez Gene 511008
UniGene Bt.55540
RefSeq NM_001103092
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02053856
GenPept
RNA Seq Atlas 511008

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca