Version 5.4
Bos taurus Gene: BT.30826
Summary
InnateDB Gene IDBG-644807.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.30826
Gene Name sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase
Synonyms siat8C
Species Bos taurus
Ensembl Gene ENSBTAG00000007347
Encoded Proteins
IDBP-697475
sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000177511:
ST8SIA3 belongs to a family of sialyltransferases that form sialyl-alpha-2,8-sialyl-R linkages at the nonreducing termini of glycoconjugates (Lee et al., 1998 [PubMed 9826427]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 24:57125861-57134072
Strand Forward strand
Band
Transcripts
ENSBTAT00000009666 ENSBTAP00000009666
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity
GO:0008373 sialyltransferase activity
GO:0016740 transferase activity
GO:0016757 transferase activity, transferring glycosyl groups
Biological Process
GO:0001574 ganglioside biosynthetic process
GO:0006486 protein glycosylation
GO:0006491 N-glycan processing
GO:0009100 glycoprotein metabolic process
GO:0009311 oligosaccharide metabolic process
GO:0097503 sialylation
Cellular Component
GO:0005794 Golgi apparatus
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030173 integral component of Golgi membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000177511
View Gene Order
ENSMUSG00000056812
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_25085
N-Glycan antennae elongation pathway
REACT_25046
Transport to the Golgi and subsequent modification pathway
REACT_22433
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
REACT_22426
Asparagine N-linked glycosylation pathway
REACT_22161
Post-translational protein modification pathway
REACT_25208
N-glycan antennae elongation in the medial/trans-Golgi pathway
REACT_22387
Synthesis of substrates in N-glycan biosythesis pathway
REACT_200874
Sialic acid metabolism pathway
REACT_17015
Metabolism of proteins pathway
REACT_198565
N-Glycan antennae elongation pathway
REACT_198566
N-glycan antennae elongation in the medial/trans-Golgi pathway
REACT_206143
Transport to the Golgi and subsequent modification pathway
REACT_248642
Synthesis of substrates in N-glycan biosythesis pathway
REACT_262413
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
REACT_247926
Metabolism of proteins pathway
REACT_236283
Post-translational protein modification pathway
REACT_237472
Asparagine N-linked glycosylation pathway
REACT_202500
Sialic acid metabolism pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1MX31
UniProt Splice Variant
Entrez Gene 414349
UniGene Bt.30826
RefSeq NM_001001599 XM_005224111
HUGO HGNC:14269
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02057149
GenPept
RNA Seq Atlas 414349

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca