Bos taurus Gene: KLF10
Summary
InnateDB Gene IDBG-645044.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KLF10
Gene Name Krueppel-like factor 10
Synonyms TIEG1
Species Bos taurus
Ensembl Gene ENSBTAG00000014396
Encoded Proteins
TGF-beta inducible early growth response protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000155090:
This gene encodes a member of a family of proteins that feature C2H2-type zinc finger domains. The encoded protein is a transcriptional repressor that acts as an effector of transforming growth factor beta signaling. Activity of this protein may inhibit the growth of cancers, particularly pancreatic cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:63951758-63957275
Strand Forward strand
Band
Transcripts
ENSBTAT00000019142 ENSBTAP00000019142
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.
Predicted by orthology
Total 20 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0030282 bone mineralization
GO:0035019 somatic stem cell maintenance
GO:0045672 positive regulation of osteoclast differentiation
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
TGF_beta_Receptor pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL A6QQG6 D0VZF7 F6QKI1
UniProt Splice Variant
Entrez Gene 522795
UniGene Bt.101967 Bt.111894
RefSeq NM_001168462
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AB530320 BC149823 DAAA02039333
GenPept AAI49824 BAI49590
RNA Seq Atlas 522795