Version 5.4
Bos taurus Gene: PXK
Summary
InnateDB Gene IDBG-645202.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PXK
Gene Name PX domain-containing protein kinase-like protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000019989
Encoded Proteins
IDBP-697892
PX domain-containing protein kinase-like protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000168297:
PXK binds to the Na,K-ATPase beta-1 (ATP1B1; MIM 182330) and beta-3 (ATP1B3; MIM 601867) subunits and modulates both Na,K-ATPase enzymatic and ion pump activities (Mao et al., 2005 [PubMed 16135750]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:43467864-43548273
Strand Reverse strand
Band
Transcripts
ENSBTAT00000030715 ENSBTAP00000030687
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0004672 protein kinase activity
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0035091 phosphatidylinositol binding
Biological Process
GO:0006468 protein phosphorylation
GO:0006954 inflammatory response
GO:0032780 negative regulation of ATPase activity
GO:0043271 negative regulation of ion transport
GO:0050804 regulation of synaptic transmission
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005815 microtubule organizing center
GO:0005886 plasma membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000168297
View Gene Order
ENSMUSG00000033885
View Gene Order
Cross-References
SwissProt
TrEMBL A5PJQ7
UniProt Splice Variant
Entrez Gene 614093
UniGene Bt.42665
RefSeq NM_001099132
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC142204 DAAA02054296 DAAA02054297
GenPept AAI42205
RNA Seq Atlas 614093

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca