InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: BT.29849

Summary

InnateDB Gene

IDBG-645217.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.29849

Gene Name

growth/differentiation factor 6 precursor

Synonyms

BMP-13; CDMP-2

Species

Bos taurus

Ensembl Gene

ENSBTAG00000007687

Encoded Proteins

IDBP-697905

growth/differentiation factor 6

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000156466:
This gene encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily of secreted signaling molecules. It is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. Mutations in this gene result in colobomata, which are congenital abnormalities in ocular development, and in Klippel-Feil syndrome (KFS), which is a congenital disorder of spinal segmentation. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 14:70399571-70416866

Strand

Forward strand

Band

Transcripts

ENSBTAT00000010110

ENSBTAP00000043329

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005125	cytokine activity
GO:0008083	growth factor activity
GO:0042803	protein homodimerization activity

Biological Process

GO:0006915	apoptotic process
GO:0007275	multicellular organismal development
GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0030509	BMP signaling pathway
GO:0032924	activin receptor signaling pathway
GO:0040007	growth
GO:0045666	positive regulation of neuron differentiation
GO:0045893	positive regulation of transcription, DNA-templated
GO:0060389	pathway-restricted SMAD protein phosphorylation