Version 5.4
Bos taurus Gene: TIPIN
Summary
InnateDB Gene IDBG-645444.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TIPIN
Gene Name TIMELESS-interacting protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000000372
Encoded Proteins
IDBP-698140
TIMELESS-interacting protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is part of the replisome complex, a group of proteins that support DNA replication. It binds TIM and aids in protecting cells against DNA damage and stress. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:13195494-13212891
Strand Reverse strand
Band
Transcripts
ENSBTAT00000000482 ENSBTAP00000000482
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0000076 DNA replication checkpoint
GO:0000077 DNA damage checkpoint
GO:0006974 cellular response to DNA damage stimulus
GO:0007049 cell cycle
GO:0007067 mitotic nuclear division
GO:0008284 positive regulation of cell proliferation
GO:0009411 response to UV
GO:0031573 intra-S DNA damage checkpoint
GO:0044770 cell cycle phase transition
GO:0048478 replication fork protection
GO:0051301 cell division
Cellular Component
GO:0000790 nuclear chromatin
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000075131
View Gene Order
ENSMUSG00000032397
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
atr_pathway
ATR signaling pathway
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.49308 Bt.96625
RefSeq NM_001105336
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca