Version 5.4
Bos taurus Gene: ID3
Summary
InnateDB Gene IDBG-645454.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ID3
Gene Name DNA-binding protein inhibitor ID-3
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000030425
Encoded Proteins
IDBP-698153
DNA-binding protein inhibitor ID-3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000117318:
The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with other HLH proteins. However, the encoded protein lacks a basic DNA-binding domain and therefore inhibits the DNA binding of any HLH protein with which it interacts. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:129895413-129897012
Strand Forward strand
Band
Transcripts
ENSBTAT00000019148 ENSBTAP00000019148
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 37 interaction(s) predicted by orthology.
Predicted by orthology
Total 37 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0019904 protein domain specific binding
GO:0046983 protein dimerization activity
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001656 metanephros development
GO:0006351 transcription, DNA-templated
GO:0007417 central nervous system development
GO:0007507 heart development
GO:0007517 muscle organ development
GO:0030855 epithelial cell differentiation
GO:0030903 notochord development
GO:0042476 odontogenesis
GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity
GO:0045662 negative regulation of myoblast differentiation
GO:0045668 negative regulation of osteoblast differentiation
GO:0045892 negative regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0015630 microtubule cytoskeleton
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000117318
View Gene Order
ENSMUSG00000007872
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_5
ID pathway
REACTOME
KEGG
hsa04350
TGF-beta signaling pathway pathway
mmu04350
TGF-beta signaling pathway pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.5230
RefSeq NM_001014950
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca