InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: BT.56405

Summary

InnateDB Gene

IDBG-645494.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.56405

Gene Name

Uncharacterized protein

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000008380

Encoded Proteins

IDBP-698214

Uncharacterized protein

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000137809:
This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein contains an I domain, is expressed in muscle tissue, dimerizes with beta 1 integrin in vitro, and appears to bind collagen in this form. Therefore, the protein may be involved in attaching muscle tissue to the extracellular matrix. Alternative transcriptional splice variants have been found for this gene, but their biological validity is not determined. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 10:15103981-15196986

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000011032

ENSBTAP00000011032

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005518	collagen binding
GO:0038064	collagen receptor activity

Biological Process

GO:0001649	osteoblast differentiation
GO:0006929	substrate-dependent cell migration
GO:0007155	cell adhesion
GO:0007160	cell-matrix adhesion
GO:0007229	integrin-mediated signaling pathway
GO:0033627	cell adhesion mediated by integrin
GO:0038065	collagen-activated signaling pathway