Version 5.4
| Bos taurus Gene: EFNA2 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-645622.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | EFNA2 | ||||||||
| Gene Name | ephrin-A2 precursor | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Gene | ENSBTAG00000038221 | ||||||||
| Encoded Proteins |
ephrin-A2
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000099617:
This gene encodes a member of the ephrin family. The protein is composed of a signal sequence, a receptor-binding region, a spacer region, and a hydrophobic region. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Posttranslational modifications determine whether this protein localizes to the nucleus or the cytoplasm. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 7:45308774-45323334 | ||||||||
| Strand | Forward strand | ||||||||
| Band | |||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
Developmental Biology pathway
Axon guidance pathway
EPHA-mediated growth cone collapse pathway
EPH-ephrin mediated repulsion of cells pathway
EPH-Ephrin signaling pathway
EPHA-mediated growth cone collapse pathway
EPH-ephrin mediated repulsion of cells pathway
EPH-Ephrin signaling pathway
Axon guidance pathway
Developmental Biology pathway
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| KEGG |
Axon guidance pathway
Axon guidance pathway
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| INOH | |||||||||
| PID NCI |
EPHA forward signaling
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| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | A5D7J8 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 614453 | ||||||||
| UniGene | Bt.5151 | ||||||||
| RefSeq | NM_001105000 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | BC140584 DAAA02020252 | ||||||||
| GenPept | AAI40585 | ||||||||
| RNA Seq Atlas | 614453 | ||||||||
| Transcript Frequencies | |||||||||
| Tag Count based mRNA-Abundances across 87 different Tissues (TPM).
Based on Data from Bovine Gene Atlas |
(Move your mouse over the image to view a more detailed version) |
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