InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: BT.102832

Summary

InnateDB Gene

IDBG-645787.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.102832

Gene Name

myosin-7

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000040053

Encoded Proteins

IDBP-698569

myosin-7

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000197616:
Cardiac muscle myosin is a hexamer consisting of two heavy chain subunits, two light chain subunits, and two regulatory subunits. This gene encodes the alpha heavy chain subunit of cardiac myosin. The gene is located ~4kb downstream of the gene encoding the beta heavy chain subunit of cardiac myosin. Mutations in this gene cause familial hypertrophic cardiomyopathy and atrial septal defect 3. [provided by RefSeq, Mar 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 10:21350297-21377051

Strand

Forward strand

Band

Transcripts

ENSBTAT00000007359

ENSBTAP00000007359

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000146	microfilament motor activity
GO:0000166	nucleotide binding
GO:0003774	motor activity
GO:0003779	actin binding
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016887	ATPase activity
GO:0019901	protein kinase binding
GO:0030898	actin-dependent ATPase activity

Biological Process

GO:0001701	in utero embryonic development
GO:0002026	regulation of the force of heart contraction
GO:0002027	regulation of heart rate
GO:0006200	ATP catabolic process
GO:0006936	muscle contraction
GO:0006941	striated muscle contraction
GO:0007512	adult heart development
GO:0007522	visceral muscle development
GO:0008016	regulation of heart contraction
GO:0008217	regulation of blood pressure
GO:0030048	actin filament-based movement
GO:0030049	muscle filament sliding
GO:0030239	myofibril assembly
GO:0030509	BMP signaling pathway
GO:0043462	regulation of ATPase activity
GO:0045214	sarcomere organization
GO:0048739	cardiac muscle fiber development
GO:0055009	atrial cardiac muscle tissue morphogenesis
GO:0055010	ventricular cardiac muscle tissue morphogenesis
GO:0060070	canonical Wnt signaling pathway
GO:0060420	regulation of heart growth