Version 5.4
Bos taurus Gene: HAUS4
Summary
InnateDB Gene IDBG-645866.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HAUS4
Gene Name HAUS augmin-like complex subunit 4
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000012723
Encoded Proteins
IDBP-698626
Uncharacterized protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000092036:
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] This gene encodes a subunit of the centrosome complex termed the human augmin complex. The encoded protein localizes to the spindle microtubules and may play a role in mitotic spindle assembly and maintenance of centrosome integrity during cell division. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:21725594-21732994
Strand Forward strand
Band
Transcripts
ENSBTAT00000016912 ENSBTAP00000016912
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 26 interaction(s) predicted by orthology.
Predicted by orthology
Total 26 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0051225 spindle assembly
GO:0051297 centrosome organization
Cellular Component
GO:0070652 HAUS complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000092036
View Gene Order
ENSMUSG00000022177
View Gene Order
Cross-References
SwissProt
TrEMBL E1BKA4
UniProt Splice Variant
Entrez Gene 614307
UniGene
RefSeq NM_001206190 XM_005211388 XM_005211389 XM_005211390 XM_005211391 XM_005211392
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02028045
GenPept
RNA Seq Atlas 614307

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca