Bos taurus Gene: IP6K1 | |||||||
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Summary | |||||||
InnateDB Gene | IDBG-645939.3 | ||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
Gene Symbol | IP6K1 | ||||||
Gene Name | inositol hexakisphosphate kinase 1 | ||||||
Synonyms | IHPK1 | ||||||
Species | Bos taurus | ||||||
Ensembl Gene | ENSBTAG00000011595 | ||||||
Encoded Proteins |
inositol hexakisphosphate kinase 1
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Protein Structure | |||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||
InnateDB Annotation from Orthologs | |||||||
Summary |
[Homo sapiens] IP6K1 disruption results in the augmentation of downstream phosphatidylinositol-(3,4,5)-triphosphate signalling in neutrophils. As a result, these neutrophils exhibited greater phagocytic and bactericidal ability and amplified NADPH oxidase-mediated production of superoxide.
[Mus musculus] Ip6k1 disruption results in the augmentation of downstream phosphatidylinositol-(3,4,5)-triphosphate signalling in neutrophils. As a result, these neutrophils exhibited greater phagocytic and bactericidal ability and amplified NADPH oxidase-mediated production of superoxide.
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Entrez Gene | |||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000176095:
This gene encodes a member of the inositol phosphokinase family. The encoded protein may be responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2011] |
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Gene Information | |||||||
Type | Protein coding | ||||||
Genomic Location | Chromosome 22:51014686-51049408 | ||||||
Strand | Forward strand | ||||||
Band | |||||||
Transcripts |
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Interactions | |||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
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Gene Ontology | |||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||
NETPATH | |||||||
REACTOME |
Synthesis of pyrophosphates in the cytosol pathway
Synthesis of IPs in the nucleus pathway
Inositol phosphate metabolism pathway
Metabolism pathway
Metabolism pathway
Synthesis of IPs in the nucleus pathway
Synthesis of pyrophosphates in the cytosol pathway
Inositol phosphate metabolism pathway
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KEGG | |||||||
INOH | |||||||
PID NCI | |||||||
Cross-References | |||||||
SwissProt | |||||||
TrEMBL | Q0II95 | ||||||
UniProt Splice Variant | |||||||
Entrez Gene | 534029 | ||||||
UniGene | Bt.46008 | ||||||
RefSeq | NM_001076010 | ||||||
HUGO | |||||||
OMIM | |||||||
CCDS | |||||||
HPRD | |||||||
IMGT | |||||||
EMBL | BC122746 DAAA02054416 | ||||||
GenPept | AAI22747 | ||||||
RNA Seq Atlas | 534029 | ||||||