Bos taurus Gene: BT.60953
Summary
InnateDB Gene IDBG-645967.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.60953
Gene Name hepatocyte growth factor-like protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000011585
Encoded Proteins
hepatocyte growth factor-like protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000173531:
The protein encoded by this gene contains four kringle domains and a serine protease domain, similar to that found in hepatic growth factor. Despite the presence of the serine protease domain, the encoded protein may not have any proteolytic activity. The receptor for this protein is RON tyrosine kinase, which upon activation stimulates ciliary motility of ciliated epithelial lung cells. This protein is secreted and cleaved to form an alpha chain and a beta chain bridged by disulfide bonds. [provided by RefSeq, Jan 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:51080758-51085659
Strand Forward strand
Band
Transcripts
ENSBTAT00000030663 ENSBTAP00000030635
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis
GO:0007566 embryo implantation
Cellular Component
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
a6b1 and a6b4 Integrin signaling
FoxO family signaling
amb2 Integrin signaling
Cross-References
SwissProt
TrEMBL E1BDW7
UniProt Splice Variant
Entrez Gene 514667
UniGene Bt.60953
RefSeq NM_001075677 XM_005222804
HUGO HGNC:7380
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02054416
GenPept
RNA Seq Atlas 514667