InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: NDUFA2

Summary

InnateDB Gene

IDBG-646070.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NDUFA2

Gene Name

NADH dehydrogenase

Synonyms

B8; CI-B8

Species

Bos taurus

Ensembl Gene

ENSBTAG00000015041

Encoded Proteins

IDBP-698843

NADH dehydrogenase

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000131495:
The encoded protein is a subunit of the hydrophobic protein fraction of the NADH:ubiquinone oxidoreductase (complex 1), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane, and may be involved in regulating complex I activity or its assembly via assistance in redox processes. Mutations in this gene are associated with Leigh syndrome, an early-onset progressive neurodegenerative disorder. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 7:53461635-53463955

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000020018

ENSBTAP00000020018

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 43 interaction(s) predicted by orthology.

Predicted by orthology
Total	43 [view]

Gene Ontology

Molecular Function

Accession

GO Term

Biological Process

GO:0055114

oxidation-reduction process

Cellular Component

GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0005747	mitochondrial respiratory chain complex I
GO:0016020	membrane
GO:0031966	mitochondrial membrane
GO:0070469	respiratory chain