Bos taurus Gene: BT.44707
Summary
InnateDB Gene IDBG-646409.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.44707
Gene Name disintegrin and metalloproteinase domain-containing protein 19 precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000003836
Encoded Proteins
disintegrin and metalloproteinase domain-containing protein 19
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000135074:
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has also been demonstrated to be an active metalloproteinase, which may be involved in normal physiological and pathological processes such as cells migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. [provided by RefSeq, May 2009]
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has been demonstrated to be an active metalloproteinase, which may be involved in normal physiological processes such as cell migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. It is proposed to play a role in pathological processes, such as cancer, inflammatory diseases, renal diseases, and Alzheimer\'s disease. [provided by RefSeq, May 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:71158812-71250704
Strand Reverse strand
Band
Transcripts
ENSBTAT00000005003 ENSBTAP00000005003
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004222 metalloendopeptidase activity
GO:0005515 protein binding
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
GO:0006509 membrane protein ectodomain proteolysis
GO:0007507 heart development
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Cross-References
SwissProt
TrEMBL F1ME22
UniProt Splice Variant
Entrez Gene 510907
UniGene Bt.44707
RefSeq NM_001075475 XM_005209671
HUGO HGNC:197
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02020794
GenPept
RNA Seq Atlas 510907