Bos taurus Gene: TSHR | |||||||||||||||||
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Summary | |||||||||||||||||
InnateDB Gene | IDBG-646909.3 | ||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||
Gene Symbol | TSHR | ||||||||||||||||
Gene Name | thyrotropin receptor precursor | ||||||||||||||||
Synonyms | |||||||||||||||||
Species | Bos taurus | ||||||||||||||||
Ensembl Gene | ENSBTAG00000017489 | ||||||||||||||||
Encoded Proteins |
thyrotropin receptor precursor
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Protein Structure | |||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||
Entrez Gene | |||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000165409:
The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008] |
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Gene Information | |||||||||||||||||
Type | Protein coding | ||||||||||||||||
Genomic Location | Chromosome 10:93417338-93571380 | ||||||||||||||||
Strand | Forward strand | ||||||||||||||||
Band | |||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||||||||||
NETPATH |
TSH pathway
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REACTOME |
G alpha (s) signalling events pathway
Hormone ligand-binding receptors pathway
Class A/1 (Rhodopsin-like receptors) pathway
Signaling by GPCR pathway
Signal Transduction pathway
GPCR downstream signaling pathway
GPCR ligand binding pathway
G alpha (s) signalling events pathway
GPCR downstream signaling pathway
Signaling by GPCR pathway
Class A/1 (Rhodopsin-like receptors) pathway
Hormone ligand-binding receptors pathway
GPCR ligand binding pathway
Signal Transduction pathway
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KEGG |
Neuroactive ligand-receptor interaction pathway
Autoimmune thyroid disease pathway
Neuroactive ligand-receptor interaction pathway
Autoimmune thyroid disease pathway
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INOH | |||||||||||||||||
PID NCI |
Arf6 trafficking events
Arf6 signaling events
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Cross-References | |||||||||||||||||
SwissProt | |||||||||||||||||
TrEMBL | F1N4F6 | ||||||||||||||||
UniProt Splice Variant | |||||||||||||||||
Entrez Gene | 281553 | ||||||||||||||||
UniGene | Bt.34 | ||||||||||||||||
RefSeq | NM_174206 XM_005212135 | ||||||||||||||||
HUGO | HGNC:12373 | ||||||||||||||||
OMIM | |||||||||||||||||
CCDS | |||||||||||||||||
HPRD | |||||||||||||||||
IMGT | |||||||||||||||||
EMBL | DAAA02029833 DAAA02029834 DAAA02029835 DAAA02029836 DAAA02029837 | ||||||||||||||||
GenPept | |||||||||||||||||
RNA Seq Atlas | 281553 | ||||||||||||||||