Version 5.4
Bos taurus Gene: CCRL1
Summary
InnateDB Gene IDBG-647339.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CCRL1
Gene Name C-C chemokine receptor type 11
Synonyms CCRL1
Species Bos taurus
Ensembl Gene ENSBTAG00000019577
Encoded Proteins
IDBP-700174
C-C chemokine receptor type 11
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000129048:
The protein encoded by this gene is a member of the G protein-coupled receptor family, and is a receptor for C-C type chemokines. This receptor has been shown to bind dendritic cell- and T cell-activated chemokines including CCL19/ELC, CCL21/SLC, and CCL25/TECK. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:138069177-138071195
Strand Reverse strand
Band
Transcripts
ENSBTAT00000026082 ENSBTAP00000026082
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004871 signal transducer activity
GO:0004930 G-protein coupled receptor activity
GO:0004950 chemokine receptor activity
GO:0005044 scavenger receptor activity
GO:0005515 protein binding
GO:0019956 chemokine binding
Biological Process
GO:0006898 receptor-mediated endocytosis
GO:0006935 chemotaxis
GO:0007165 signal transduction
GO:0007186 G-protein coupled receptor signaling pathway
GO:0070098 chemokine-mediated signaling pathway
Cellular Component
GO:0005768 endosome
GO:0005769 early endosome
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0055037 recycling endosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000129048
View Gene Order
ENSMUSG00000079355
View Gene Order
Pathways
NETPATH
REACTOME
REACT_219025
Peptide ligand-binding receptors pathway
REACT_205369
Signaling by GPCR pathway
REACT_214353
Signal Transduction pathway
REACT_220217
GPCR ligand binding pathway
REACT_208412
Class A/1 (Rhodopsin-like receptors) pathway
REACT_212617
Chemokine receptors bind chemokines pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_15344
Chemokine receptors bind chemokines pathway
REACT_14819
Peptide ligand-binding receptors pathway
REACT_14828
Class A/1 (Rhodopsin-like receptors) pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_21340
GPCR ligand binding pathway
REACT_254215
Signaling by GPCR pathway
REACT_261161
Class A/1 (Rhodopsin-like receptors) pathway
REACT_231468
GPCR ligand binding pathway
REACT_235286
Peptide ligand-binding receptors pathway
REACT_230248
Chemokine receptors bind chemokines pathway
REACT_188257
Signal Transduction pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt P35350
TrEMBL
UniProt Splice Variant
Entrez Gene 281672
UniGene Bt.565
RefSeq NM_174265
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC142169 S63848
GenPept AAB27547 AAI42170
RNA Seq Atlas 281672

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca