InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: CLDN2

Summary

InnateDB Gene

IDBG-647507.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CLDN2

Gene Name

Claudin-2

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000005290

Encoded Proteins

IDBP-700327

Claudin-2

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000165376:
This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.[provided by RefSeq, Jan 2010]
This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5\' untranslated region have been found for this gene.[provided by RefSeq, Jan 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome X:60134287-60136956

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000006960

ENSBTAP00000006960

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005198	structural molecule activity
GO:0005515	protein binding
GO:0042802	identical protein binding

Biological Process

GO:0016338

calcium-independent cell-cell adhesion

Cellular Component

GO:0005886	plasma membrane
GO:0005923	tight junction
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030054	cell junction
GO:0070062	extracellular vesicular exosome