Bos taurus Gene: BT.91603 | |||||||
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Summary | |||||||
InnateDB Gene | IDBG-647769.3 | ||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
Gene Symbol | BT.91603 | ||||||
Gene Name | 40S ribosomal protein S6 | ||||||
Synonyms | |||||||
Species | Bos taurus | ||||||
Ensembl Gene | ENSBTAG00000005315 | ||||||
Encoded Proteins |
40S ribosomal protein S6
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Protein Structure | |||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||
Entrez Gene | |||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000137154:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||
Type | Protein coding | ||||||
Genomic Location | Chromosome 2:111820296-111821112 | ||||||
Strand | Reverse strand | ||||||
Band | |||||||
Transcripts |
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Interactions | |||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 130 interaction(s) predicted by orthology.
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Gene Ontology | |||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||
NETPATH |
KitReceptor pathway
BCR pathway
IL2 pathway
Leptin pathway
TSH pathway
TSLP pathway
FSH pathway
Prolactin pathway
IL11 pathway
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REACTOME |
L13a-mediated translational silencing of Ceruloplasmin expression pathway
S6K1 signalling pathway
S6K1-mediated signalling pathway
mTOR signalling pathway
PI3K Cascade pathway
Signaling by Insulin receptor pathway
IRS-related events triggered by IGF1R pathway
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) pathway
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) pathway
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) pathway
GTP hydrolysis and joining of the 60S ribosomal subunit pathway
Translation initiation complex formation pathway
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S pathway
Formation of a pool of free 40S subunits pathway
Formation of the ternary complex, and subsequently, the 43S complex pathway
Ribosomal scanning and start codon recognition pathway
Eukaryotic Translation Termination pathway
Peptide chain elongation pathway
Eukaryotic Translation Elongation pathway
SRP-dependent cotranslational protein targeting to membrane pathway
Viral mRNA Translation pathway
Eukaryotic Translation Initiation pathway
Influenza Infection pathway
PKB-mediated events pathway
Nonsense-Mediated Decay (NMD) pathway
mTORC1-mediated signalling pathway
Influenza Viral RNA Transcription and Replication pathway
Translation pathway
Signal Transduction pathway
IRS-mediated signalling pathway
Metabolism of proteins pathway
Insulin receptor signalling cascade pathway
Cap-dependent Translation Initiation pathway
IRS-related events pathway
IGF1R signaling cascade pathway
Influenza Life Cycle pathway
Gene Expression pathway
Disease pathway
Peptide chain elongation pathway
Signaling by Insulin receptor pathway
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S pathway
S6K1 signalling pathway
Translation pathway
Eukaryotic Translation Termination pathway
Translation initiation complex formation pathway
Nonsense-Mediated Decay (NMD) pathway
Metabolism of proteins pathway
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) pathway
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) pathway
Cap-dependent Translation Initiation pathway
Eukaryotic Translation Initiation pathway
Insulin receptor signalling cascade pathway
S6K1-mediated signalling pathway
IRS-related events triggered by IGF1R pathway
IGF1R signaling cascade pathway
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) pathway
PI3K Cascade pathway
SRP-dependent cotranslational protein targeting to membrane pathway
Eukaryotic Translation Elongation pathway
Formation of a pool of free 40S subunits pathway
Gene Expression pathway
IRS-related events pathway
IRS-mediated signalling pathway
mTORC1-mediated signalling pathway
L13a-mediated translational silencing of Ceruloplasmin expression pathway
Signal Transduction pathway
Ribosomal scanning and start codon recognition pathway
mTOR signalling pathway
PKB-mediated events pathway
GTP hydrolysis and joining of the 60S ribosomal subunit pathway
Formation of the ternary complex, and subsequently, the 43S complex pathway
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KEGG |
mTOR signaling pathway pathway
Ribosome pathway
Insulin signaling pathway pathway
Insulin signaling pathway pathway
mTOR signaling pathway pathway
Ribosome pathway
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INOH |
Insulin receptor signaling pathway
Insulin receptor signaling pathway
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PID NCI |
ErbB1 downstream signaling
IL2 signaling events mediated by PI3K
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Cross-References | |||||||
SwissProt | |||||||
TrEMBL | F1MKZ5 | ||||||
UniProt Splice Variant | |||||||
Entrez Gene | 787914 | ||||||
UniGene | Bt.7908 Bt.91603 | ||||||
RefSeq | |||||||
HUGO | |||||||
OMIM | |||||||
CCDS | |||||||
HPRD | |||||||
IMGT | |||||||
EMBL | DAAA02006023 | ||||||
GenPept | |||||||
RNA Seq Atlas | 787914 | ||||||