Bos taurus Gene: BT.30825 | |||||||||||||
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Summary | |||||||||||||
InnateDB Gene | IDBG-647797.3 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | BT.30825 | ||||||||||||
Gene Name | C-C chemokine receptor type 8 | ||||||||||||
Synonyms | |||||||||||||
Species | Bos taurus | ||||||||||||
Ensembl Gene | ENSBTAG00000015483 | ||||||||||||
Encoded Proteins |
Chemokine C-C motif receptor 8Uncharacterized protein
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Protein Structure | |||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
Entrez Gene | |||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000179934:
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||
Type | Protein coding | ||||||||||||
Genomic Location | Chromosome 22:12678580-12679638 | ||||||||||||
Strand | Forward strand | ||||||||||||
Band | |||||||||||||
Transcripts |
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Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||||||
NETPATH | |||||||||||||
REACTOME |
G alpha (i) signalling events pathway
Chemokine receptors bind chemokines pathway
Peptide ligand-binding receptors pathway
Class A/1 (Rhodopsin-like receptors) pathway
Signaling by GPCR pathway
Signal Transduction pathway
GPCR downstream signaling pathway
GPCR ligand binding pathway
GPCR downstream signaling pathway
Signaling by GPCR pathway
G alpha (i) signalling events pathway
Signal Transduction pathway
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KEGG |
Cytokine-cytokine receptor interaction pathway
Chemokine signaling pathway pathway
Cytokine-cytokine receptor interaction pathway
Chemokine signaling pathway pathway
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INOH | |||||||||||||
PID NCI | |||||||||||||
Cross-References | |||||||||||||
SwissProt | |||||||||||||
TrEMBL | F6RDR3 Q6PVA0 | ||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | 407772 | ||||||||||||
UniGene | Bt.108246 Bt.30825 | ||||||||||||
RefSeq | NM_001194962 XM_005222374 XM_005222375 | ||||||||||||
HUGO | HGNC:1609 | ||||||||||||
OMIM | |||||||||||||
CCDS | |||||||||||||
HPRD | |||||||||||||
IMGT | |||||||||||||
EMBL | AY575856 DAAA02053670 | ||||||||||||
GenPept | AAT01443 | ||||||||||||
RNA Seq Atlas | 407772 | ||||||||||||