InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: CLDN5

Summary

InnateDB Gene

IDBG-647913.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CLDN5

Gene Name

Claudin-5

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000022020

Encoded Proteins

IDBP-700699

Claudin-5

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000184113:
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 17:74749250-74750524

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000029418

ENSBTAP00000029418

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005198	structural molecule activity
GO:0005515	protein binding

Biological Process

Cellular Component

GO:0005886	plasma membrane
GO:0005911	cell-cell junction
GO:0005923	tight junction
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030054	cell junction
GO:0070062	extracellular vesicular exosome