Version 5.4
Bos taurus Gene: CLDN9
Summary
InnateDB Gene IDBG-648696.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CLDN9
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000047563
Encoded Proteins
IDBP-701414
claudin 9
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000213937:
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This protein is one of the entry cofactors for hepatitis C virus. Mouse studies revealed that this gene is required for the preservation of sensory cells in the hearing organ and the gene deficiency is associated with deafness. [provided by RefSeq, Jun 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 25:2433850-2434503
Strand Forward strand
Band
Transcripts
ENSBTAT00000065513 ENSBTAP00000056359
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005198 structural molecule activity
Biological Process
GO:0045216 cell-cell junction organization
Cellular Component
GO:0005886 plasma membrane
GO:0005923 tight junction
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030054 cell junction
Orthologs
Species
Mus musculus
Homo sapiens
Gene ID
Gene Order
ENSMUSG00000066720
View Gene Order
ENSG00000213937
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_19373
Tight junction interactions pathway
REACT_111155
Cell-Cell communication pathway
REACT_20676
Cell junction organization pathway
REACT_19331
Cell-cell junction organization pathway
KEGG
mmu04530
Tight junction pathway
mmu04514
Cell adhesion molecules (CAMs) pathway
mmu04670
Leukocyte transendothelial migration pathway
mmu05160
Hepatitis C pathway
hsa04514
Cell adhesion molecules (CAMs) pathway
hsa04670
Leukocyte transendothelial migration pathway
hsa04530
Tight junction pathway
hsa05160
Hepatitis C pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL G3N384
UniProt Splice Variant
Entrez Gene 617449
UniGene
RefSeq XM_002697935 XM_869712
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02057322 GJ062847
GenPept DAA15709
RNA Seq Atlas 617449
Transcript Frequencies
Tag Count based mRNA-Abundances across 87 different Tissues (TPM).

Based on Data from Bovine Gene Atlas

Tag Count based mRNA-Abundances across 87 different Tissues (TPM)

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If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca