Bos taurus Gene: BT.88403
Summary
InnateDB Gene IDBG-648941.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.88403
Gene Name cytochrome c oxidase subunit 8A, mitochondrial precursor
Synonyms COX8; COX8L
Species Bos taurus
Ensembl Gene ENSBTAG00000004920
Encoded Proteins
cytochrome c oxidase subunit 8A, mitochondrial precursor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000176340:
The protein encoded by this gene is the terminal enzyme of the respiratory chain, coupling the transfer of electrons from cytochrome c to molecular oxygen, with the concomitant production of a proton electrochemical gradient across the inner mitochondrial membrane. In addition to 3 mitochondrially encoded subunits, which perform the catalytic function, the eukaryotic enzyme contains nuclear-encoded smaller subunits, ranging in number from 4 in some organisms to 10 in mammals. It has been proposed that nuclear-encoded subunits may be involved in the modulation of the catalytic function. This gene encodes one of the nuclear-encoded subunits. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:24442440-24442887
Strand Forward strand
Band
Transcripts
ENSBTAT00000006474 ENSBTAP00000048633
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004129 cytochrome-c oxidase activity
Biological Process
GO:1902600 hydrogen ion transmembrane transport
Cellular Component
GO:0005739 mitochondrion
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Respiratory electron transport pathway
Transmembrane transport of small molecules pathway
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. pathway
Orphan transporters pathway
The citric acid (TCA) cycle and respiratory electron transport pathway
Metabolism pathway
The citric acid (TCA) cycle and respiratory electron transport pathway
Orphan transporters pathway
Respiratory electron transport pathway
Metabolism pathway
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. pathway
Transmembrane transport of small molecules pathway
KEGG
Alzheimer's disease pathway
Oxidative phosphorylation pathway
Parkinson's disease pathway
Huntington's disease pathway
Cardiac muscle contraction pathway
Oxidative phosphorylation pathway
Alzheimer's disease pathway
Parkinson's disease pathway
Cardiac muscle contraction pathway
Huntington's disease pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E1BH77
UniProt Splice Variant
Entrez Gene 783202
UniGene Bt.88403
RefSeq NM_174024 XM_001251833 XM_003587523
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02050357
GenPept
RNA Seq Atlas 281091 783202