Version 5.4
Homo sapiens Gene: GRIPAP1
Summary
InnateDB Gene IDBG-65007.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GRIPAP1
Gene Name GRIP1 associated protein 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000068400
Encoded Proteins
IDBP-65021
GRIP1 associated protein 1
IDBP-810403
GRIP1 associated protein 1
IDBP-810405
GRIP1 associated protein 1
IDBP-810408
GRIP1 associated protein 1
IDBP-810419
GRIP1 associated protein 1
IDBP-810420
GRIP1 associated protein 1
IDBP-810421
GRIP1 associated protein 1
IDBP-810422
GRIP1 associated protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a guanine nucleotide exchange factor for the Ras family of small G proteins (RasGEF). In brain studies, the encoded protein was found with the GRIP/AMPA receptor complex. Multiple alternatively spliced transcript variants have been described that encode different protein isoforms; however, the full-length nature and biological validity of all of these variants have not been determined.[provided by RefSeq, Nov 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome X:48973720-49002264
Strand Reverse strand
Band p11.23
Transcripts
ENST00000376423 ENSP00000365606
ENST00000473581
ENST00000488361
ENST00000474512
ENST00000480041
ENST00000495258
ENST00000619149
ENST00000593475 ENSP00000469842
ENST00000622599 ENSP00000477574
ENST00000619107 ENSP00000480856
ENST00000611757
ENST00000621664 ENSP00000480180
ENST00000622231 ENSP00000482629
ENST00000617369 ENSP00000480042
ENST00000611705 ENSP00000479263
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005769 early endosome
GO:0072562 blood microparticle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000031153
View Gene Order
ENSBTAG00000007788
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 56850
UniGene
RefSeq NM_020137
HUGO HGNC:18706
OMIM 300408
CCDS CCDS35248
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas 56850

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca