Version 5.4
Homo sapiens Gene: LRRC32
Summary
InnateDB Gene IDBG-65186.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LRRC32
Gene Name leucine rich repeat containing 32
Synonyms D11S833E; GARP
Species Homo sapiens
Ensembl Gene ENSG00000137507
Encoded Proteins
IDBP-65188
leucine rich repeat containing 32
IDBP-294334
leucine rich repeat containing 32
IDBP-294332
leucine rich repeat containing 32
IDBP-381266
leucine rich repeat containing 32
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a type I membrane protein which contains 20 leucine-rich repeats. Alterations in the chromosomal region 11q13-11q14 are involved in several pathologies. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:76657524-76670747
Strand Reverse strand
Band q13.5
Transcripts
ENST00000260061 ENSP00000260061
ENST00000407242 ENSP00000384126
ENST00000404995 ENSP00000385766
ENST00000421973 ENSP00000413331
ENST00000464145
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0010628 positive regulation of gene expression
GO:0046007 negative regulation of activated T cell proliferation
GO:0050710 negative regulation of cytokine secretion
Cellular Component
GO:0005887 integral component of plasma membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000090958
View Gene Order
ENSBTAG00000001301
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.151641
RefSeq NM_001128922 NM_005512 XM_005273902 XM_005273903
HUGO
OMIM
CCDS CCDS8245
HPRD 00667
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca