Version 5.4
Homo sapiens Gene: NDUFC2
Summary
InnateDB Gene IDBG-65848.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NDUFC2
Gene Name NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa
Synonyms B14.5b; CI-B14.5b; HLC-1; NADHDH2
Species Homo sapiens
Ensembl Gene ENSG00000151366
Encoded Proteins
IDBP-65850
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa
IDBP-593990
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa
IDBP-591476
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa
IDBP-599439
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa
IDBP-586526
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This locus represents naturally occurring read-through transcription between the neighboring NDUFC2 (NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa) and KCTD14 (potassium channel tetramerisation domain containing 14) genes on chromosome 11. The read-through transcripts share sequence identity with the upstream gene product and one variant has a frameshifted C-terminal region derived from the downstream gene exons. [provided by RefSeq, Feb 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:78068304-78080219
Strand Reverse strand
Band q14.1
Transcripts
ENST00000281031 ENSP00000281031
ENST00000527806 ENSP00000432739
ENST00000534029 ENSP00000432253
ENST00000525085 ENSP00000434262
ENST00000528164 ENSP00000435017
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008137 NADH dehydrogenase (ubiquinone) activity
Biological Process
GO:0006120 mitochondrial electron transport, NADH to ubiquinone
GO:0022904 respiratory electron transport chain
GO:0044237 cellular metabolic process
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005743 mitochondrial inner membrane
GO:0005747 mitochondrial respiratory chain complex I
GO:0016021 integral component of membrane
GO:0070469 respiratory chain
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000030647
View Gene Order
ENSBTAG00000018188
Not yet available
Pathways
NETPATH
REACTOME
REACT_22393
Respiratory electron transport pathway
REACT_6305
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. pathway
REACT_111083
The citric acid (TCA) cycle and respiratory electron transport pathway
REACT_111217
Metabolism pathway
KEGG
hsa05010
Alzheimer's disease pathway
hsa00190
Oxidative phosphorylation pathway
hsa05012
Parkinson's disease pathway
hsa05016
Huntington's disease pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.407860
RefSeq NM_001204054 NM_001204055 NM_004549
HUGO
OMIM
CCDS CCDS55779 CCDS55781 CCDS8257
HPRD 11960
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca