Version 5.4
Homo sapiens Gene: GOLGA3
Summary
InnateDB Gene IDBG-65969.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GOLGA3
Gene Name golgin A3
Synonyms GCP170; MEA-2
Species Homo sapiens
Ensembl Gene ENSG00000090615
Encoded Proteins
IDBP-65971
golgin A3
IDBP-385315
golgin A3
IDBP-385317
golgin A3
IDBP-807090
golgin A3
IDBP-586565
golgin A3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes a member of the golgin family of proteins which are localized to the Golgi. Its encoded protein has been postulated to play a role in nuclear transport and Golgi apparatus localization. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Feb 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:132768909-132828858
Strand Reverse strand
Band q24.33
Transcripts
ENST00000204726 ENSP00000204726
ENST00000450791 ENSP00000410378
ENST00000456883 ENSP00000409303
ENST00000541013 ENSP00000479170
ENST00000537452
ENST00000537317
ENST00000534967
ENST00000545875 ENSP00000442603
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 21 [view]
Protein-Protein 20 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0005515 protein binding
Biological Process
GO:0006891 intra-Golgi vesicle-mediated transport
Cellular Component
GO:0000139 Golgi membrane
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0016020 membrane
GO:0017119 Golgi transport complex
GO:0032580 Golgi cisterna membrane
GO:0090498 extrinsic component of Golgi membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000029502
View Gene Order
ENSBTAG00000009755
Not yet available
Cross-References
SwissProt Q08378
TrEMBL
UniProt Splice Variant
Entrez Gene 2802
UniGene Hs.507333 Hs.714198 Hs.737975
RefSeq NM_001172557 NM_005895 XM_005266162 XM_005266164 XM_005266165 XM_005266167 XM_006719736 XM_006719737 XM_006719738 XM_006719739 XM_006719740
HUGO HGNC:4426
OMIM 602581
CCDS CCDS53846 CCDS9281
HPRD 03990
IMGT
EMBL AB027133 AF485338 BC060826 BC142658 BC146675 D63997 L06148
GenPept AAA35921 AAH60826 AAI42659 AAI46676 AAL93149 BAA23661 BAB71953
RNA Seq Atlas 2802

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca